Clinical Infectious Diseases ; Carbapenem gene regions of these isolates are given in Figure 1. Search and download doctoral PHD dissertations from Sweden. The primers used in this study are listed in Table 2. Data analysis The Fisher’s Exact Test were performed for all clinical data.
BioMed Research International, ; Transcription of the genes encoding penicillin-binding 2 and 3 PBP-2 and -3 was studied in some of the isolates. Johan Tham ; Lunds universitet. Consequently, results demonstrated that virulence factors, antibiotic resistance, porin loss, multi drug efflux pump and quorum sensing molecules should be considered collective manner in the further studies about bacterial pathogenesis for developing effective treatments. On the other hand, carbapenem resistant E.
Found 3 swedish dissertations containing the words carbapenem resistant enterobacteriaceae. How to cite reesistance article. Extended-release ciprofloxacin as a novel treatment option. The least common virulence gene region among strains is hly gene region responsible for hemolysis.
Virulence factors and drug resistance in Escherichia coli isolated from extraintestinal infections. DNA sequence analysis of the composite plasmid pTC conferring virulence and antimicrobial resistance for porcine enterotoxigenic Escherichia crabapenem. Demir M, Kaleli I. Also, serotype O12 isolates from Greece harboring genes encoding different VIM-variants were found to belong to the same sequence type.
Characteristics of Carbapenem Resistance and Virulence Factors. Aerobactin and ferric aerobactin expressed by a er and iutA gene regions are important siderophores in E.
PCR products were analyzed by electrophoresis in a 1. The results of the study appear to indicate that fimA and afa genes correlate with carbapenem susceptibility, the relations of fimA with urinary tract infections and pap with complicated urinary tract infections.
Phylogenetic diversity of Escherichia coli strains producing NDM-type carbapenemases. Naas T, Nordmann P. A new quorum-sensing inhibitor attenuates virulence and decreases antibiotic resistance in Pseudomonas aeruginosa. Extended-spectrum beta-lactamases ESBL which hydrolyze penicillins, cephalosporins, monobactams and generally inhibited by beta-lactamase inhibitors such as clavulanic acid, sulbactam and tazobactam can be produced by the members of Enterobacteriaceae.
In this study, when the carbapenem and virulence gene profiles are evaluated and 24 types of virulence profiles are identified Table 3. Down-regulation of OprD, which is the primary porin for carbapenem uptake, confers resistance to both imipenem and meropenem, although the latter is affected less.
carbapenfm In total, 50 Escherichia coli strains were identified by microbiology standard methods and chromogenic medium. The primers used in this study are listed in Table 1.
Clinical Microbiology Reviews ; Johan Tham ; Lunds universitet. ABSTRACT In this study, fifty Escherichia coli strains were analyzed by multiplex polymerase chain reaction for the genes expressed carbapenemase and virulence factors in order to determine the presence of carbapenemase and nine virulence factors and investigate the association between these two characteristics.
Marlen Adler ; Uppsala universitet. The data of this study have been excerpted from the PhD thesis of the author. These gene regions are shown in Figure 2. Siderophores in urinary tract infections are virulence factors frequently found disswrtation most pathogenic types of E. Indian Journal of Medical Microbiology ; Popular dissertations yesterday Broadband Wireless OFDM Systems Combinatorics and zeros of multivariate polynomials Compact sprawl Exploring public open space and contradictions in urban density Analysis and human levels of persistent perfluorinated chemicals Clinical, epidemiological and immunological aspects of Lyme borreliosis with special focus on the role of the complement system Strategic Management of Customer Relationships-A Network Perspective on Key Account Management The carbapenfm link in learning in science centres Resistancd Languages, Translating Bodies Approaches to Speech, Translation and Cultural Identity in Early European Sound Ersistance Landfill gas emission and landfill vegetation Assessment of human exposure to per- and polyfluorinated compounds PFCs: Great diversity of virulence in urine isolates were observed, whereas any virulence gene is not found in catheter.
Only meropenem is a substrate for the efflux pumps, due to the absence of a resiztance side chain in the chemical structure of imipenem. Carbapenemase; Escherichia coli; multiplex polymerase chain reaction; virulence factor.
Therefore, determining of beta-lactam group resistance, these mechanisms should be taken into consideration. Journal of Hospital Infection ; Data analysis The Fisher’s Exact Dissertarion were performed for all clinical data.
Multiplex PCR analysis of carbapenemase gene regions The reaction conditions were modified from Poirel et al.